Thursday 5th January 2012

GeneGnome used for Seven Years at Top Pharmacology Department To Help Study Proteins Associated with Cell Signalling

Syngene is delighted to announce its GeneGnome chemiluminescence imaging system has been used by scientists at the UK’s University of Cambridge for seven years to help understand how proteins in cell signalling are expressed.

Researchers in the Department of Pharmacology at the University of Cambridge are using a GeneGnome dedicated chemiluminescence imager to analyse proteins on Western blots stained with SuperSignal or ECL™. The information from the blots is helping to determine how the receptor proteins are regulated and its aim is to lead to a better understanding of the role of receptor proteins in aspects of cellular activity as varied as programmed cell death and muscle contraction.

Dr Emily Taylor, Laboratory Manager in the Department of Pharmacology commented: “We have had the GeneGnome for seven years and we chose to install this system because we knew Syngene had a good reputation for service. Since the GeneGnome only does one thing, it is easy to operate and even when you have different sized blots, it will automatically focus the blot image for you. We have detected large membrane proteins of 260 KDa and visualised nanogram amounts of protein, so it has plenty of sensitivity for our work.”

Laura Sullivan, Syngene’s Divisional Manager, added: “We are delighted to see our GeneGnome contributing to an understanding of protein expression in cell signalling. Having scientists at a top pharmacology department use our GeneGnome so regularly for seven years is a testament to the system’s robust, reliable performance.”


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